Important safety information
What you should know before taking Zepbound®. Please see the full Prescribing Information for complete safety information.
Zepbound® (tirzepatide)
Help address menopausal weight gain with Zepbound®
Control appetite
Regulate blood sugar
Improve body composition
Weight loss that’s optimized for midlife
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Weight FAQ
Zepbound® is a brand name version of the medication tirzepatide, the same active ingredient contained in Mounjaro®. It is FDA-approved for chronic weight management in adults who meet certain medical criteria. Zepbound® works differently than semaglutide medications because it activates two hormone receptors (GLP-1 and GIP), which enhances its effects on weight loss. Like other weight medications, Zepbound® is most effective when combined with diet and exercise.
Zepbound® is a dual-agonist medication that activates both GLP-1 and GIP receptors. By mimicking these hormones, it reduces hunger, increases feelings of fullness, and slows digestion. Zepbound® also improves insulin sensitivity and lowers glucagon levels, helping to regulate blood sugar and support weight loss.
To access care on Evernow click Get Care or Get Started. You'll begin by sharing a bit about your health history, symptoms and primary goals, including your interest in Zepbound. Once you select your membership plan, we'll give you the choice of how to connect with your Evernow provider. We offer insurance-covered video visits and unlimited text messaging. Together, you'll develop a personalized care plan tailored to your needs. Any medications you are prescribed can be sent to your local pharmacy or delivered at-home. Your provider will work with you to obtain any necessary labs or additional medical information related to your care.
At Evernow, you can utilize insurance to help cover some aspects of your care. On video visits, we accept insurance from top U.S. health plans, including United Healthcare, Aetna, Anthem, and Blue Cross Blue Shield. Any medications you are prescribed at Evernow may also be covered by any commercial insurance if fulfilled through your local pharmacy. Most expenses are FSA/HSA eligible. If you have any additional questions, our support team may be able to help.
When starting Zepbound®, most patients will begin with a lower dose and gradually increase it over the first few months until a steady dose is reached. This approach helps your body adjust to the medication and any potential side effects. Your healthcare provider will work with you to determine the best dosing schedule for you, based on your individual response and tolerance. Results vary, but clinical trials of tirzepatide have shown an average weight loss of 20% total body weight when combined with diet and exercise.
Common side effects of Zepbound® may include nausea, diarrhea, decreased appetite, vomiting, constipation, indigestion, and stomach pain. While these side effects are typically mild, it's important to be aware of some serious risks, such as thyroid tumors, pancreatitis, low blood sugar, and severe allergic reactions. Contact your healthcare provider if you experience symptoms like swelling in your neck, persistent stomach pain, or changes in vision.
Zepbound® is a once weekly medication that comes in a prefilled injection pen that contains multiple doses. The pen is designed to help ease administration and minimize discomfort. If prescribed, you (or someone in your household) will select the prescribed dose and administer the injection under the skin of your abdomen, upper thigh or upper arm. While some patients may experience a mild pinprick sensation or slight skin irritation at the injection site, these effects are typically minimal. Follow your healthcare provider's instructions on administration.
Zepbound® and Wegovy® are both FDA-approved for weight loss. Ozempic® is FDA-approved for managing type 2 diabetes and may be prescribed off label for weight loss. The key difference lies in the active ingredient. Zepbound® contains tirzepatide, which activates two hormone receptors—GLP-1 and GIP—to regulate metabolism and enhance feelings of fullness. In contrast, Ozempic® and Wegovy® contain semaglutide, which only activates the GLP-1 receptor. This dual action makes tirzepatide unique and may contribute to greater weight loss.
At Evernow, we're committed to helping you access the weight loss treatments that suit your needs. Our team works closely with you to navigate the path to coverage, ensuring you get the support you need from your healthcare provider and our Care Team. While name-brand GLP-1 medications like Ozempic® and Wegovy® may be in short supply, our providers will help you explore all available options to continue your weight loss journey confidently. We strive to make high-quality treatments accessible, even during times of medication shortages, so you can achieve your health goals.